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Describe the events of the relaxation period of a muscle twitch.

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During relaxation, tension decreases as ...

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Latrotoxin, produced by the poisonous black widow spider, increases the release of acetylcholine. How do muscle cells respond?


A) Muscle cells will twitch irregularly when excess acetylcholine exists.
B) Muscle cells will experience fused or complete tetanus when excess acetylcholine exists.
C) Muscle cells will become paralyzed when excess acetylcholine exists.
D) Muscle cells will experience a longer latent period when excess acetylcholine exists.

E) A) and B)
F) C) and D)

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Which of the following promotes the depolarization stage?


A) opening of voltage -gated potassium ion channels and potassium ions exit the cell
B) closure of voltage -gated sodium ion channels
C) hydrolysis of ATP
D) opening of voltage -gated sodium ion channels and sodium ions enter the cell

E) A) and D)
F) All of the above

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What does the depolarization of the transverse tubules (T -tubules) promote?


A) release of acetylcholine from vesicles in the motor neuron into the synaptic cleft
B) binding of acetylcholine to ligand -gated sodium ion channels
C) entry of sodium ions into the muscle fiber through voltage -gated sodium ion channels
D) release of calcium from the sarcoplasmic reticulum

E) All of the above
F) C) and D)

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When a skeletal muscle fiber contracts:


A) Z discs move farther apart while the A bands shorten.
B) the H zone and I bands narrow.
C) the A bands shorten while the I bands lengthen.
D) the H zone narrows while the I bands widen.

E) All of the above
F) A) and D)

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Type I fibers lack:


A) a blood supply.
B) myoglobin.
C) mitochondria.
D) speed.

E) A) and D)
F) A) and B)

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What happens when troponin and tropomyosin block the active sites of actin?


A) The muscle produces a weak contraction.
B) The muscle relaxes.
C) The muscle contraction reaches peak tension.
D) The muscle contraction increases tension.

E) A) and B)
F) All of the above

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A muscle cell experiencing resting membrane potential is:


A) propagating an action potential.
B) more negatively charged on its exterior than in its interior.
C) experiencing depolarization.
D) polarized.

E) B) and C)
F) B) and D)

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During excitation -contraction coupling, calcium ion concentration is highest in the:


A) terminal cisterna.
B) sarcolemma.
C) sarcoplasmic reticulum.
D) cytosol of the muscle fiber.

E) All of the above
F) C) and D)

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Describe the role of calcium in the crossbridge cycle of the sliding filament mechanism.

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Calcium ions released from the sarcoplas...

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Define excitability.

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Excitability is the ...

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ATP is required for a power stroke to be repeated during the contraction cycle.

A) True
B) False

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What part of the myofibril shortens to produce contractions of the muscle fiber?


A) myosin filaments
B) A band
C) sarcomere
D) elastic filaments

E) A) and B)
F) B) and D)

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The three types of myofilaments are thin, thick and elastic.

A) True
B) False

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What do skeletal muscle tissue and cardiac muscle tissue share in common?


A) Both skeletal and cardiac muscle tissues perform peristalsis.
B) Both skeletal and cardiac muscle tissues possess intercalated discs.
C) Both skeletal and cardiac muscle tissues are striated.
D) Both skeletal and cardiac muscle tissues are voluntary.

E) A) and C)
F) B) and C)

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A triad consists of:


A) actin filaments, troponin, and tropomyosin.
B) myosin filaments, myosin heads, and myosin tails.
C) a transverse tubule (T -tubule) and two terminal cisternae.
D) a fascicle of skeletal muscle cells and its surrounding perimysium.

E) None of the above
F) C) and D)

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Which protein does NOT belong in a thin filament?


A) troponin
B) tropomyosin
C) myosin
D) actin

E) B) and C)
F) All of the above

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The fastest muscle contraction would be produced by a:


A) type IIc fiber.
B) type IIb fiber.
C) type IIx fiber.
D) type I fiber.

E) B) and C)
F) B) and D)

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How does hypertrophy change a muscle? Briefly explain.

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Hypertrophy is an in...

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The plasma membrane of a muscle cell is known as the:


A) myofibril.
B) sarcolemma.
C) sarcoplasmic reticulum.
D) sarcomere.

E) B) and C)
F) All of the above

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