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Uric acid produced by insect Malpighian tubules does not influence the movement of water from the hindgut because:


A) it is eliminated by the tubules before water reaches the hindgut.
B) it precipitates due to the low pH of the fluid and therefore does not contribute to osmotic pressure.
C) water moves only in response to the osmotic pressure created by proteins and sugars in the hindgut.
D) uric acid is equally concentrated in the hindgut and in the body fluids.
E) None of the answer options is correct.

F) B) and E)
G) A) and E)

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Which of the following is an advantage of producing very concentrated urine?


A) minimizing water loss
B) reducing the need to drink
C) ability to live in drier environments
D) All of these choices are correct.

E) B) and C)
F) A) and B)

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One of the roles of the kidneys is to help buffer body fluids so that they are not too acidic or too basic. The cells of the renal tubule secrete H+ into the tubule lumen, and absorb bicarbonate (HCO3-), passing it into the tissue fluid. Consider the reaction catalyzed by the enzyme carbonic anhydrase, shown in the accompanying figure and below. One of the roles of the kidneys is to help buffer body fluids so that they are not too acidic or too basic. The cells of the renal tubule secrete H<sup>+</sup> into the tubule lumen, and absorb bicarbonate (HCO<sub>3</sub><sup>-</sup>), passing it into the tissue fluid. Consider the reaction catalyzed by the enzyme carbonic anhydrase, shown in the accompanying figure and below.   During heavy exercise, the reaction shifts to the right in the nephron (lumen of the tubule). During heavy exercise, the reaction shifts to the right in the nephron (lumen of the tubule).

A) True
B) False

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Which of the following statements is NOT true?


A) Excretion of urea requires less water than excretion of uric acid.
B) Urea is produced in the liver and eliminated in the kidneys.
C) Uric acid can be stored at a higher concentration in tissues than urea.
D) Ammonia is lethal to cells at high concentrations.
E) Excretion of ammonia requires high volumes of water in the surrounding environment.

F) B) and E)
G) A) and E)

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ADH controls how diluted or concentrated urine is by controlling the permeability of the:


A) collecting ducts to water.
B) collecting ducts to electrolytes.
C) collecting ducts to urea.
D) loops of Henle to water.
E) loops of Henle to electrolytes.

F) A) and B)
G) A) and C)

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Which of the following statements about Malpighian tubules is CORRECT?


A) All these choices are correct.
B) They are a series of tubes that empty into the hindgut of insects.
C) They actively secrete uric acid and excess electrolytes while retaining key solutes.
D) They allow insects to live in dry terrestrial environments.
E) They allow nitrogenous wastes to be excreted with minimal water loss.

F) B) and E)
G) A) and E)

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Metanephridia differ from protonephridia in all of the following ways EXCEPT that:


A) the urine produced in both systems is more dilute than the body fluids.
B) metanephridia are surrounded by an extensive capillary network, whereas protonephridia are not.
C) selective reabsorption of materials occurs via cells lining the tubules in protonephridia and via capillaries in metanephridia.
D) fluid enters metanephridia through a funnel-shaped opening.
E) fluid from the body cavity enters protonephridia without first being filtered.

F) D) and E)
G) B) and D)

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Water moves from regions of:


A) high water concentration to regions of low water concentration.
B) low water concentration to regions of high water concentration.
C) high solute concentration to regions of low solute concentration.
D) low solute concentration to regions of high solute concentration.
E) low water concentration to regions of low solute concentration.

F) B) and C)
G) A) and C)

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The majority of fluid that enters the nephron:


A) moves into the loop of Henle.
B) is reabsorbed by the proximal convoluted tubule.
C) exits the nephron through the collecting duct.
D) is reabsorbed by the descending loop of Henle.

E) B) and C)
F) C) and D)

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The first part of the renal tubule is called the _____ and is specialized for _____.


A) proximal convoluted tubule; reabsorption of electrolytes and other nutrients
B) loop of Henle; creation of a concentration gradient in the interstitial fluid
C) distal convoluted tubule; secretion of additional wastes into the urine
D) distal convoluted tubule; reabsorption of water
E) collecting duct; reabsorption of water

F) D) and E)
G) C) and D)

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Which of the following structures are NOT associated with ion regulation in animals?


A) nasal salt glands
B) Malpighian tubules
C) tear ducts
D) kidneys

E) B) and C)
F) A) and D)

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The specialized salt glands that allow marine birds to drink seawater are found in the nasal cavity; in humans, these glands are found in the esophagus.

A) True
B) False

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Which of the following statements about osmoconformers is FALSE?


A) They do not have to adapt to the solute concentrations in the external environment.
B) Their internal osmotic pressure matches that of the surrounding environment.
C) They often actively regulate the concentrations of particular ions in their body fluids.
D) They use less energy to regulate osmotic pressure than osmoregulators.
E) Most marine invertebrates are osmoconformers.

F) D) and E)
G) A) and D)

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The loop of Henle is a countercurrent exchanger because it creates a concentration gradient rather than simply maintaining it.

A) True
B) False

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Nephrons:


A) extend from the cortex into the medulla.
B) are located entirely within the cortex.
C) are located entirely within the medulla.
D) are located within the renal pelvis.
E) None of the answer options is correct.

F) None of the above
G) A) and B)

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In the vertebrate kidney, reabsorption and secretion take place in the renal tubules; after that, the filtrate enters the collecting ducts as _____.

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Which large group of animals consists largely of osmoconformers?


A) marine invertebrates
B) bony fish
C) mammals
D) insects
E) amphibians

F) D) and E)
G) B) and C)

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Most mammals excrete _____; most aquatic animals excrete _____; birds, insects, and many reptiles excrete _____.


A) uric acid; urea; ammonia
B) uric acid; ammonia; urea
C) urea; uric acid; ammonia
D) urea; ammonia; uric acid
E) ammonia; urea; uric acid

F) B) and C)
G) C) and E)

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The mammalian kidney has an outer layer called the _____ and an inner layer called the _____.


A) cortex; medulla
B) pelvis; glomerulus
C) epithelium; endothelium
D) medulla; pelvis
E) glomerulus; cortex

F) A) and D)
G) C) and D)

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Nitrogenous wastes are produced through the breakdown of which of the following?


A) proteins
B) glucose
C) lipids
D) carbohydrates
E) All of these choices are correct.

F) A) and B)
G) A) and C)

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